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Downloading Rosetta: "Forbidden. You don't have permission...."

Submitted by kmyers2 on Fri, 2024-04-05 14:24
Category: 
Compilation

hi! i'm trying to download Rosetta as an academic user. Whenever I attempt to download Rosetta (Software > License & Download > Academic Download > Download Rosetta 3.14 or any of the releases), I get an error saying "Forbidden. You don't have permission to access /downloads/academic/3.14 on this server." I tried reaching out to the CoMotion people at UW, and they said they cannot help and to ask here. How do I get access to download Rosetta? I keep looking for a license agreement i need to fill out or something but can't find anything. Thank you!

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Rosetta 3 - Build/Install

Issues with compilation on MacOS

Submitted by olivia.macleod on Fri, 2024-04-05 07:52
Category: 
Compilation

Hi, I am having difficult with downloading and compiling the academic version of Rosetta from github (but perhaps that is the wrong way to do it by cloning it onto my Desktop - MacOS 14.4). I tried to compile using scons and it seemed to work following the full instructions, but I noticed I do not have a rosetta/main/ folder. I found a rosetta/source/bin folder and compiled into that source folder. Is that correct? I can now see a number .macosclangrelease files. Thank you. 

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Rosetta 3 - Build/Install

Model GFP chromophore(cro) using NCAA or NC backbone method?

Submitted by lei on Thu, 2024-04-04 06:23
Category: 
Chemically Modified Residues

Dear users,

Because GFP chromophore (CRO) comes from cyclization of three amino acids: S, Y, and G, I am not sure how to model it.

(1) In "Using NCAAs in Protein-Peptide Interface Design", Ornithine can be seen as a modified form of Lys: only one amino acid.

However, CRO includes three amino acids, so there are total three R groups. When preparing rotamer library, CHI angles from three R groups seems confusing.

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Rosetta 3 - Applications

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