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PyRosetta Setup

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PyRosetta Setup

Mac OS Catalina 10.15.5

Python 3.7


Hello, I am having trouble setting up PyRosetta after it is installed on my computer. I have unpacked it but when I try to do - cd setup && sudo python install - in command line it asks for a password. The password I was given with my academic license does not work. Any help or guidance would be much appreciated.

Post Situation: 
Thu, 2020-07-02 15:01

I'm not sure if this is your issue, but the username and password for PyRosetta is different from the username and password for regular Rosetta. You can't interchange them. If you got a plain Rosetta license & password, go to and request a PyRosetta license as well.  -- That's probably not the case though, if you successfully downloaded it. (The password is for download access.)

The other possibility is that you're trying to install PyRosetta to the system Python installation. In that case, you may need to authenticate with your system using a proper administator password. I'm not too familiar with Macs, but if you have administrator rights on the machine, I believe it's asking for your regular Mac user account login password.

If you don't have administrator rights on the machine, you may need to install PyRosetta into your home directory, instead of the system location. I believe that can be accomplished by adding `--user` to the command line.

Thu, 2020-07-09 10:50