I'm brand new to the forums and a beginner at using Rosetta. I've got what may be a very simple or a very complicated question. I would like to dock a relatively small protein into a symmetrical complex with known symmetry and structure. At first, I saw the Symmetrical Docking protocol and thought that might be what I should use, but that seems to be for docking the members of the complex together, not for docking a different protein into the complex, and I'd imagine the scoring would be more complicated in this case. Has anyone done this before, can Rosetta do this, and if so, could someone steer me in the right direction? Thanks so much!
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Docking a protein into a symmetrical complex