You are here

conda installation

4 posts / 0 new
Last post
conda installation

Dear friends,

I am new to rosetta and need some help. Basically, I have two questions:

1) My main interest is to use rosettafold to predict structures. Do I need to install pyrosetta for this purpose?

2) I was trying to install pyrosetta through conda. According to the instruction, I need to put "" in the .condarc file. Where should I obtain the usr/psw? I registered for rosetta and received an email containing a usr/psw with usr is "Academic_User". I can use them to download rosetta from However, when I put them in the .condarc file and tried, I got the following error from conda: 
"The credentials you have provided for this URL are invalid"

Thank you very much.


Post Situation: 
Fri, 2021-07-30 13:16

Hello Michael.

1) yes.

2) you can request an academic license specific for pyrosetta via the 'comotion' site:

Let me know if you encounter any further issues!

Sun, 2021-08-01 00:47

Thank you very much for your help! With your help I realized the license I requested is for rosetta not pyrosetta!

Can you brief me what is the difference between rosetta, pyrosetta, and rosettafold? 

Thank you very much.



Sun, 2021-08-01 17:26


PyRosetta is a Python-script based front-end to the Rosetta molecular modeling suite. Rosetta, which is a collaborative project between more than 15 labs world-wide, requires users to have substantial experience in C++ and Rosetta software development to write custom algorithms. Through the use of Python-bindings to Rosetta C++ source code, PyRosetta allows the end-user to have access to the same Rosetta functions available to Rosetta developers, through an easy-to-use Python script based interface.


RoseTTAFold is the Baker-Lab attempt to reproduce the results of DeepMind's AlphaFold pipeline using Rosetta tools, introducing deep neural networks.

Sun, 2021-08-08 01:17