Hello Everyone,
In the User Guide: Ab Initio Structure Prediction it says that
......Additionally you often know information about the environment your protein exists or will exist in that is not yet taken into account by the energy function, such as boundaries on size and position of particular residue or atoms. Constrainst allow you to take advantage of such specialized knowledge....
Does anyone know how you go about set up constrainst on the size of particular residues? I am interested in mimicking the effect of glycosylating my Ser/Thr residues by increasing the volume of the centriods that represent they side chains.
Thank you all in advance
Aaron T. Frank
In the User Guide: Ab Initio Structure Prediction it says that ......Additionally you often know information about the environment your protein exists or will
> Hello Everyone,
>
> In the User Guide: Ab Initio Structure Prediction it says that
> ......Additionally you often know information about the environment your protein exists or will exist in that is not yet taken into account by the energy function, such as boundaries on size and position of particular residue or atoms. Constrainst allow you to take advantage of such specialized knowledge....
>
> Does anyone know how you go about set up constrainst on the size of particular residues? I am interested in mimicking the effect of glycosylating my Ser/Thr residues by increasing the volume of the centriods that represent they side chains.
>
> Thank you all in advance
> Aaron T. Frank