You are here

what kind of focefield does Rosetta based on?

2 posts / 0 new
Last post
what kind of focefield does Rosetta based on?
#1

what kind of focefield does Rosetta based on? I read all possible manuals of i Rosetta website and didn't find any answear about this question.

Does anybody know?

Thank you very much.

Tue, 2010-07-06 11:08
albumns

Start here:

Methods Enzymol. 2004;383:66-93.
Protein structure prediction using Rosetta.

Rohl CA, Strauss CE, Misura KM, Baker D.

PMID: 15063647 [PubMed]

http://www.ncbi.nlm.nih.gov/pubmed/15063647

and here:

Science. 2003 Nov 21;302(5649):1364-8.
Design of a novel globular protein fold with atomic-level accuracy.

Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D.
http://www.ncbi.nlm.nih.gov/pubmed/14631033

This describes most of the scorefunction terms as of 7 years ago. Their base forms haven't changed much although they've been tweaked.

I don't think we've published a review of the scorefunction since 3.0, but if I forgot one someone please correct me. There's a major review of the overhauls in the 3.x series that's been submitted but it doesn't talk about the scorefunction forms, since they didn't change much.

Wed, 2010-07-07 07:16
smlewis