I am interested in changing the psi-psi angles of two residues in a turn. When I use set_phi/set_psi command to change the angles, it completely disrupts the structure. Is there any way to only change the dihedral of those two residues alone without changing/disrupting the structure. I tried the same thing in Pymol, but there also I get the same disrupted structure. Can anybody suggest some other tool ??
Is it wrong to change dihedral angles of certain region and freeze the other regions of protein ??