I am new to rosetta, so can someone help me to figure out how to do ab-initio for a subunit in a multimeric protein.
I am interested in doing ab-initio for one subunit whose crystal structure is not known and the crystal structures of other non-covalently interacting subunits are completely known. It is experimentally known that the subunit whose crystal structure is not known is predominantly helix and also the approximate position of the helix is also known.
Please help me!!!