Thank you for the informations in this forum which already helped me a lot. I have a question concerning constraints/restraints in RosettaCM. I want to predict the structure of a protein from which I know templates for two domains and several intramolecular crosslinks/distances between residues. As far as I understood only one template can be used for comparative modelling in the minirosetta application, so I chose RosettaCM for this chain.
How do I include the restraints in the best way?
I found the Mover 'ConstraintSetMover' and added it in my xml-file but I don't really get how to do it in the best way, whether to use filters (does the filter ResidueDistance have something to do with it) or movers (eg AddConstraintsToCurrentConformationMover
?) and which one of them.
My restraints are atompairs for which I know the distance, I uploaded the xml-script.
Thank you a lot,