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Rosetta Holes

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Rosetta Holes

Dear Rosetta Users:

I would like to use the rosetta holes application to evaluate the packing of my protein. But the documentation for this aplication is not in great details. I have been searching posted questions about rosetta holes from the forum and it seems that this app has been in and out of the rosetta suite. So I am wondering if the rosetta holes is currently available in the most updated rosetta version and if there is a general guide on how to use this application.

Thank you very much!

Best regards,


Post Situation: 
Wed, 2015-09-30 11:40

RosettaHoles is unfortunately one of our under-documented features. The best documentation we have would be the Sheffler et al. papers and the associated Supplemental Material, if any.

One of the main applications for RosettaHoles (holes.linuxgccrelease) is not currently in the public release version of Rosetta, although a number of other protocols and RosettaScripts filters (like the undocumented HolesFilter and the minimally documented InterfaceHoles filter ( ) access the same machinery, and can get you some information on it.

Mon, 2015-10-12 15:20