I have a question about the RosettaCM Monte-Carlo sampling. I know, that it is not a problem with a program, so it is not for forum, but I hope for the best!
In the article it is written that "A Monte Carlo trajectory is carried out with two types of moves. (1) Substitution of the backbone torsion angles of a randomly selected Rosetta de novo fragment for the current torsion angles of these residues, and regeneration of coordinates according to the fold tree".
However, I from this article I couldn't understand where the "current torsion angles" come from? Do they run molecular dynamics which create new conformation with new torsion angles?
Thank you in advance,