Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery.
Latest News
Speed Up PyRosetta Development with Autocompletion and Type Checking
By Harrison Truscott PyRosetta, the Python interface to the Rosetta binary, now comes packaged with…
A Zero-Shot Approach to de novo Metalloenzyme Design
Key Takeaways: dEVA (design by EVolutionary Algorithm) is a framework that achieves the zero-shot design…
Immunogen Design Workshop Hosted by the Meiler Lab Cultivated Collaborations
On April 13 – 15, 2026, fifteen participants from as far away as South Korea…
Deep Learning’s Impact on de novo Protein Design
Key Takeaways: With advancements in AI, the field of protein engineering has shifted from template-based…
Next Generation Generative Model Unlocks de novo Designs at Scale
Key Takeaways: NVIDIA’s new Proteina-Complexa model combines generative AI with inference-time search algorithms to operate…
ML Protein Design Bootcamp Now Available on YouTube
Hosted in November 2025 by the University of California Davis, this course provides a practical,…
Let’s Get Social: New Ways to Connect with @RosettaCommons
Rosetta Commons is a community based on sharing scientific discoveries and fostering collaborations to advance…
RFD3 Tutorials Are Here!
We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in…
Megathon 2026: One week, Two Hackathons, 10 Tutorials, and 16 Curated Datasets
Against a backdrop of blue skies, green palm trees, and white sandy beaches, Megathon 2026…
Upcoming Events
Summer RosettaCon 2026 is on August 3 - 7, 2026, at the University of Washington in Seattle, WA.
European RosettaCon is October 28 - 30, 2026, at NOVA University Lisbon in Portugal.