Advancing biomolecular science through open collaboration

Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery.

Latest News

Rosetta Commons Postbaccalaureate Trainees: Primed and Ready

November 13, 2026

  Featured image of the 2026 – 2027 Rosetta Commons Postbaccalaureate program trainees alongside program…

Integrating Ion Mobility Data with Rosetta and AlphaFold Resolves Complex Structural Assembly Challenges

November 12, 2026

Key Takeaways Combining low-resolution structural data from ion mobility mass spectrometry with computational docking tools…

Empowering the Next Generation of Computational Scientists: Highlights from Our August 2026 Workshops

November 6, 2026

Featured image is a group photo of the Leipzig Rosetta Workshop 2026 participants, tutors, and organizers.…

RFD4-Proteina Improves Computational Protein Design through Open Science and Collaboration

October 23, 2026

Collaboration across the biomolecular modeling and design community continues to drive scientific advancements and discoveries.…

Introducing Chaperone: A Unified Framework for Protein Design Workflows

October 19, 2026

Protein design workflows bring together multiple tools for generating protein structures, designing sequences, predicting structures,…

Introducing makeshift: Bringing Biomolecular NMR and Dynamics Analysis into Python

October 15, 2026

Key Takeaways makeshift is an open-source Python package that streamlines retrieving, curating, and analyzing biomolecular…

High-Throughput Protein Purification: From Linear DNA to Pure Protein in Three Days

October 5, 2026

Key Takeaways An engineered His-tagged SUMO protease was developed to release SUMO-tagged proteins directly from…

How to Build a Model with AtomWorks: A Step-by-Step Guided Tutorial

September 29, 2026

Whether you’re training your first machine learning model or your tenth, preparing your data and…

Science, Connection, and Community: Summer RosettaCon 2026 Recap

September 25, 2026

Featured image is a group photo of Summer RosettaCon 2026 in-person attendees. With over 600…

Upcoming Events

Winter RosettaCon 2027, in partnership with Keystone Symposia, is on March 29 - April 1, 2027 at La Fonda on the Plaza in Santa Fe, New Mexico.

Summer RosettaCon is August 9 - 13, 2026, at the University of Washington in Seattle, Washington.