Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery.
Latest News
Deep Learning’s Impact on de novo Protein Design
Key Takeaways: With advancements in AI, the field of protein engineering has shifted from template-based…
Next Generation Generative Model Unlocks de novo Designs at Scale
Key Takeaways: NVIDIA’s new Proteina-Complexa model combines generative AI with inference-time search algorithms to operate…
ML Protein Design Bootcamp Now Available on YouTube
Hosted in November 2025 by the University of California Davis, this course provides a practical,…
Let’s Get Social: New Ways to Connect with @RosettaCommons
Rosetta Commons is a community based on sharing scientific discoveries and fostering collaborations to advance…
RFD3 Tutorials Are Here!
We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in…
Megathon 2026: One week, Two Hackathons, 10 Tutorials, and 16 Curated Datasets
Against a backdrop of blue skies, green palm trees, and white sandy beaches, Megathon 2026…
Rosetta Commons Run (rc-run) Now Available
We are pleased to announce a new Rosetta Commons workflow optimization tool: rc-run. rc-run (invoked…
Registrations are now open for European RosettaCon 2026
The registrations for the 5th European RosettaCon – Crossing Boundaries with Protein Design, taking place…
Summer RosettaCon 2026 registration is now open
We are pleased to announce that Summer RosettaCon 2026 will take place at the University…
CyclicMPNN adapts sequence design to cyclic backbones
Why this work matters Cyclic peptides are attractive scaffolds because their closed backbone can promote…
Upcoming Events
Summer RosettaCon 2026 is on August 3 - 7, 2026, at the University of Washington in Seattle, WA.
European RosettaCon is October 28 - 30, 2026, at NOVA University Lisbon in Portugal.