Advancing biomolecular science through open collaboration

Summer RosettaCon 2026 registration is now open!

Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery.

Latest News

RFD3 Tutorials Are Here!

March 20, 2026

We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in…

Megathon 2026: One week, Two Hackathons, 10 Tutorials, and 16 Curated Datasets

March 19, 2026

Against a backdrop of blue skies, green palm trees, and white sandy beaches, Megathon 2026…

Rosetta Commons Run (rc-run) Now Available

March 18, 2026

We are pleased to announce a new Rosetta Commons workflow optimization tool: rc-run. rc-run (invoked…

Registrations are now open for European RosettaCon 2026

March 11, 2026

The registrations for the 5th European RosettaCon – Crossing Boundaries with Protein Design, taking place…

Foundry Docker Image Now Available

February 25, 2026

Rosetta Commons now offers an official Foundry Docker image designed to make it dramatically easier…

Summer RosettaCon 2026 registration is now open

February 25, 2026

We are pleased to announce that Summer RosettaCon 2026 will take place at the University…

CyclicMPNN adapts sequence design to cyclic backbones

February 25, 2026

Why this work matters Cyclic peptides are attractive scaffolds because their closed backbone can promote…

Angela Colbert joins Rosetta Commons as Communications Lead

February 25, 2026

Angela Colbert, Ph.D., joined us on February 23 as our new Communications Lead. She comes…

Engineering a protein biosensor to detect common NSAIDs in wastewater

February 25, 2026

Why this research matters Pharmaceuticals often end up in wastewater after use, and monitoring them…

Registration open: Immunogen design workshop at Vanderbilt

February 25, 2026

The Meiler Lab at Vanderbilt University will host an in-person workshop, Computationally Guided Immunogen Design…

Featured story

AtomWorks & RosettaFold3 (in ModelForge) now open-source on GitHub

Sep 15, 2025

We’re excited to share that two major repositories are live on the RosettaCommons GitHub: AtomWorks and ModelForge.  AtomWorks is a broadly applicable data framework for…

Upcoming Events

Summer RosettaCon 2026 is on Augsut 3 - 7, 2026, at the University of Washington in Seattle, WA.

workshop covers

European RosettaCon is October 28 - 30, 2026, at NOVA University Lisbon in Portugal.