Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery.
Latest News
Brazil’s Largest Open Science Event Introduces Thousands to Protein Design with Foldit
For the second year in a row, Brazil’s largest open science event introduced thousands of…
Motivated Trainees and Tutors Shine at FEBS Advanced Practical Course
On April 19-24, 2026, 36 international participants gathered in Blankenberge, Belgium, for the FEBS Advanced…
Debating the balance between model openness and biosecurity guardrails
Key Takeaways The scientific community is currently debating how to balance open research with biosecurity…
Biohub releases open source models that utilize evolution to design disease target binders
Key Takeaways Biohub has released open source ESM protein language models that use evolutionary data…
OpenBind releases initial structure and affinity dataset for structure-based machine learning
Key Takeaways OpenBind is generating dense, high-quality protein-ligand datasets that link structural data with binding…
Summer 2026 Workshop Registrations Now Open
Two exciting week-long workshops this summer are now accepting applications. On July 20 – 24,…
Speed Up PyRosetta Development with Autocompletion and Type Checking
By Harrison Truscott PyRosetta, the Python interface to the Rosetta binary, now comes packaged with…
A Zero-Shot Approach to de novo Metalloenzyme Design
Key Takeaways: dEVA (design by EVolutionary Algorithm) is a framework that achieves the zero-shot design…
Immunogen Design Workshop Hosted by the Meiler Lab Cultivated Collaborations
On April 13 – 15, 2026, fifteen participants from as far away as South Korea…
