Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery.
Latest News
Bridging Borders in Protein Design in Latin America – The AI4PD Workshop in Patagonia
Puerto Varas, Chile — in November, the stunning landscapes of Chilean Patagonia, including the Llanquihue…
Designing new enzymes around catalytic arrays with Riff-Diff
Markus Braun, Adrian Tripp, and colleagues from the Oberdorfer lab at Graz University of Technology…
RFdiffusion3 is Now Available in foundry
The RFdiffusion3 (RFD3) training and inference code is now available through foundry. This third-generation model…
RFAntibody creates epitope-specific antibody binders with atomic-level agreement
Designing antibodies that bind a specific epitope normally requires immunization or screening millions of variants.…
Neil King named Deputy Director of UW’s Institute for Protein Design
The Institute for Protein Design (IPD) at the University of Washington has announced new leadership…
RFDpoly for design of RNA, DNA, and biopolymers is now available on GitHub
RFDpoly is a generative diffusion framework for the design of de novo biopolymers such as…
Two Rosetta community talks now live on TED
Two talks from our community — one by César Ramírez‑Sarmiento and one by Chris Bahl…
Congratulations to Tanja Kortemme on her NIH Award on biological error correction
We’re excited to share that Tanja Kortemme has received a major NIH award for her…
Announcing the 2025–2027 Rosetta Commons Executive Board
We are pleased to share the results of the recent Rosetta Commons Executive Board election…
RoseTTAFold2-PPI: Predicting Protein Interactions with AI
Researchers at Qian Cong’s Lab have released RoseTTAFold2-PPI, a deep-learning model designed to predict how…
Featured story
AtomWorks & RosettaFold3 (in ModelForge) now open-source on GitHub
Sep 15, 2025
We’re excited to share that two major repositories are live on the RosettaCommons GitHub: AtomWorks and ModelForge. AtomWorks is a broadly applicable data framework for…
Upcoming Events
Rosetta Megathon (Mega-Hackathon) is on March 2-6, 2026, in San Juan, Puerto Rico
Summer RosettaCon 2026 is on Aug 3-7, 2026, at the University of Washington in Seattle, WA.