Enzyme Design
Submitted by bharat_46010 on Tue, 2014-11-25 23:55
Category:
Enzyme Design
Hi,
I would like to know whether the enzyme design protocol of Rosetta Suite can be used for increasing the catalytic activity of the enzyme. Here, I don't have to design the active site from scratch, but I need to design the active site in such a way so that the catalytic activity of the enzyme is increased. Also, the enzyme I am dealing with does not have data for transition state modeling for the substrate that I am dealing with.
Please provide you comments and suggestions
Thanks
--
BH
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