I don't have experimental data on the disordered region of a protein and tried different online prediction servers and obtained contradictory results. Disopred2 was used in the Wang et al PLoS 2011 rosetta paper but I am not sure about the accuracy. I was wondering if there were any suggestions on how to proceed?
Thanks a priori.
I am Ray Wang. I would do parallel modeling runs with disordered regions predicted by different methods, and then see which ones give you make-sense convergent results.
Will try. Thanks Ray!