Rosetta Commons Run (rc-run) Now Available

We are pleased to announce a new Rosetta Commons workflow optimization tool: rc-run.

rc-run (invoked as rc) is a command-line utility tool for running containerized and native biomolecular software. It simplifies common tasks, such as mounting local directories, building HPC containers, running containerized applications, and logging executed commands, to make complex workflows easier to reliably run and reproduce. rc-run gives the user the choice of how to run the apps, whether through using docker, HCP containers, or native runs without virtualization at all.

With the goal of becoming a seamless part of your daily computational workflow, we welcome community feedback on additional tools or applications that you would like rc-run to support, including software not developed by Rosetta Commons.

Repository and documentation: https://github.com/RosettaCommons/rc

Currently supported apps: Rosetta, PyRosetta, RFDiffusion, ProteinMPNN, LigandMPNN, Foundry (RFDiffusion3, ProteinMPNN, RosettaFold3)

Supported Execution Modes