Hi all,
I'm currently trying to run the CCDLoopClosureMover function in order to attach two protein domains together.
When I try to add a single cutpoint variant around my jump point, I repeatedly get a warning that says:
"Residue 126 is not compatible with cutpoints; variant type not changed."
Residue 126 is the Cterminus
This warning also shows up for residue 127 (the Nterminus of the other protein domain). And thus, I cannot apply CCD to my pose because I don't have a cutpoint variant....
I can't seem to find anything on the internet about this issue, any help would be greatly appreciated.
Category:
Post Situation:
You want to remove the C-terminus variant.
core.pose.remove_variant_type_from_residue
You'll need to pass the variant type as an enum, the list of which is located at core.chemical.VariantType; the terminal variant will be: LOWER_TERMINUS_VARIANT, the N-teminus will have the UPPER_TERMINUS_VARIANT, that will need to be removed. That should allow you to add the cutpoint variants, which CCD needs.
It worked! Thank you!!