Latest News
Summer RosettaCon 2026 registration is now open
We are pleased to announce that Summer RosettaCon 2026 will take place at the University of Washington in Seattle from August 3–7, 2026. The conference…
CyclicMPNN adapts sequence design to cyclic backbones
Why this work matters Cyclic peptides are attractive scaffolds because their closed backbone can promote structural rigidity and proteolytic stability. Yet assigning sequences that reliably…
Angela Colbert joins Rosetta Commons as Communications Lead
Angela Colbert, Ph.D., joined us on February 23 as our new Communications Lead. She comes to us from NASA’s Jet Propulsion Laboratory, where she spent…
Foundry Docker Image Now Available
Rosetta Commons now offers an official Foundry Docker image designed to make it dramatically easier to run cutting-edge biomolecular machine learning models without complex setup.…
Engineering a protein biosensor to detect common NSAIDs in wastewater
Why this research matters Pharmaceuticals often end up in wastewater after use, and monitoring them can be technically demanding. Traditional analytical methods are powerful but…
Registration open: Immunogen design workshop at Vanderbilt
The Meiler Lab at Vanderbilt University will host an in-person workshop, Computationally Guided Immunogen Design with Rosetta and ML Tools, on April 13–15, 2025. The…
Documentation Playbook Now Available
The Documentation Playbook is a new guide designed to make writing and maintaining documentation for your software projects clearer and easier. The Documentation Playbook is…
Ultra-large virtual screening using a motif-guided Rosetta pipeline validated in zebrafish
Broader significance: a screenable path from computation to in vivo Virtual screening can now evaluate billions of molecules. But that scale creates a practical problem.…
Using protein design experiments to guide energy-function development
Why this matters When a protein is designed on a computer, tiny “impossible overlaps” between atoms can slip into the model. Those clashes may look…