we can specific the number of target structures for the script to design via the
-jd2: ntrials X
flag where X is the number.
However, in the GenericMonteCarlo mover used for iterative design, we can also specify the number of iterations via the "trials" argument.
My question is, are there any advantages/disadvantages to setting the nstruct number low but setting the trials number high, and vice versa?
My intuition is that if nstruct is low and trials is high, you will get a small number of designs with a high degree of convergence, whereas if you set nstruct high and trials low, you will get a large library of structures, but a lot of them won't necessarily have the best scores. Is this interpretation correct?
What values do people typically use here?