Dock cyclic peptide with non-canonical amino acids to protein target using rosetta flexpepdock?
Dear Rosetta users,
Is it possible that we could use Rosetta flexpepdock to dock a cyclic peptide (backbone cycle, disulfide cycle, or chemical linker cycle) with non-canonical amino acids to protein target?
It seems we could model the structures for such cyclic peptide with non-canonical amino acids using Rosetta, but I am not sure their docking methods.
If not, could you please recommend a docking program in Rosetta or other software for this application?
Thanks!