News from RC
RFdiffusion3 is Now Available in foundry
The RFdiffusion3 (RFD3) training and inference code is now available through foundry. This third-generation model builds on RFdiffusion1 and RFdiffusion2, expanding the scope of what diffusion models can design. RFD3: Performs atom-level diffusion across both backbone and side-chain atoms Has a new denoising procedure that incorporates a forward step without conditioning information Restores symmetry design…
Read MoreNeil King named Deputy Director of UW’s Institute for Protein Design
The Institute for Protein Design (IPD) at the University of Washington has announced new leadership updates. Neil King, an Associate Professor in the Department of Biochemistry, has been appointed Deputy Director of IPD. Meanwhile, Lance Stewart, formerly Interim Executive Director (and earlier Chief Strategy & Operations Officer), is retiring from the organization. The Institute’s longtime…
Read MoreCongratulations to Tanja Kortemme on her NIH Award on biological error correction
We’re excited to share that Tanja Kortemme has received a major NIH award for her project “De novo design and engineering of biological error correction.” Biology achieves extreme fidelity in processes critical for life—such as DNA replication and protein translation—using non-equilibrium kinetic proofreading, which amplifies correct over incorrect molecular outcomes by orders of magnitude. This…
Read MoreAnnouncing the 2025–2027 Rosetta Commons Executive Board
We are pleased to share the results of the recent Rosetta Commons Executive Board election for the 2025–2027 term. Thank you to everyone in the community who participated and helped shape our shared direction. 2025–2027 Executive Board TJ Burnett, Treasurer Alena Khmelinskaia, Early Career Faculty Chair David Nannemann, Industry Chair Clara Schoeder, Documentation Chair Colin…
Read MoreRoland Dunbrack Receives ASBMB DeLano Award
Rosetta Commons is delighted to celebrate Roland L. Dunbrack, Jr., recipient of the ASBMB DeLano Award for Computational Biosciences. This award honors scientists whose computational methods make molecular and cellular research both innovative and broadly accessible. Established in memory of Warren L. DeLano, the creator of PyMOL, it recognizes work that accelerates discovery across the…
Read MoreNew Docker Images on Rosetta Commons DockerHub
We are excited to announce that Rosetta Commons supported Docker images for RFdiffusion, ProteinMPNN, and LigandMPNN are now available on DockerHub! We hope that these images will make it easier to Try them out, share your feedback, and help us keep improving open science tools! Is there another tool from our community you would like…
Read MoreRosetta Commons Opens Applications for 2025 Biosecurity Fellow
Rosetta Commons is now accepting applications for our next Biosecurity Fellow! This unique 12-month fellowship offers the opportunity to work at the intersection of computational protein design and biosecurity policy. Fellows will engage with leading scientists and contribute to the responsible development of AI-enabled design tools. The inaugural fellowship led to events like the Responsible…
Read MoreWelcome Rachel Clune and Hope Woods to the Open Rosetta Team!
We are delighted to share the addition of two new members to the Open Rosetta team at OMSF. Please join us in welcoming Rachel Clune as our new Documentation Writer, starting on May 1, and Hope Woods as our new Technical Product Lead, starting on May 12. Rachel Clune brings a wealth of experience in…
Read MoreIntroducing Rosetta Commons Research Experience for Undergraduates (REU) cohort 2025
We’re pleased to introduce the 2025 Rosetta Commons Research Experience for Undergraduates (REU) cohort. Interns in this REU program, which is hosted across multiple locations, engage in research using the Rosetta Commons software. This software library provides tools for computational modeling and analysis of protein structures. It has supported major scientific progress in computational biology,…
Read MoreA Landmark Year for the Rosetta Commons REU Program
This year, the Rosetta Commons Research Experience for Undergraduates (REU) program received a record-breaking 613 applications—more than any year in its history. As a long-standing program committed to training the next generation of leaders in biomolecular modeling and design, this moment marks both a milestone and a reflection of growing global interest in the field.…
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