Latest News
Science & Tools
Introducing makeshift: Bringing Biomolecular NMR and Dynamics Analysis into Python
Key Takeaways makeshift is an open-source Python package that streamlines retrieving, curating, and analyzing biomolecular Nuclear Magnetic Resonance (NMR) data…
High-Throughput Protein Purification: From Linear DNA to Pure Protein in Three Days
Key Takeaways An engineered His-tagged SUMO protease was developed to release SUMO-tagged proteins directly from nickel-charged magnetic beads. This on-bead…
Two-phase computational pipeline yields high-affinity de novo BMP-2 binders for bone regeneration
Key Takeaways By combining Rosetta-based motif grafting with deep-learning tools like RFdiffusion, ProteinMPNN, and AlphaFold2, a two-phase approach successfully generated…
Documentation & Tutorials
How to Build a Model with AtomWorks: A Step-by-Step Guided Tutorial
Whether you’re training your first machine learning model or your tenth, preparing your data and building the infrastructure around your…
ML Protein Design Bootcamp Now Available on YouTube
Hosted in November 2025 by the University of California Davis, this course provides a practical, beginner-friendly overview of modern AI/ML…
RFD3 Tutorials Are Here!
We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in the Foundry documentation! Whether you’re…
Events
Science, Connection, and Community: Summer RosettaCon 2026 Recap
Featured image is a group photo of Summer RosettaCon 2026 in-person attendees. With over 600 in-person and virtual attendees, 56…
REU Trainees’ Research Projects Highlight Exciting First Steps in Biomolecular Research
REU trainee Tony Peonio presenting his lightning talk at Summer RosettaCon 2026. This is part three of a three part…
A Summer of Science: REU Trainees Conduct Research at Host Labs, Present at Summer RosettaCon 2026
Featured image is the 2026 REU cohort with Program Manager Camille Mathis and PI Jeffrey Gray. This is part two…
Community News
Reflections on Rosetta Commons’ Inaugural Biosecurity Fellowship
In October 2023, then-U.S. President Biden signed an Executive Order on the Safe, Secure, and Trustworthy Development and Use of…
Our First Nobel: Rosetta Members Celebrate in Stockholm
“Scientific breakthroughs do not happen in isolation; progress depends on the collective contributions of many.” — David Baker, 2024 Nobel…
Lab exchange in Rosetta community
I am a postdoc in my final year in Prof. Bill DeGrado’s lab. During one of our weekly meetings, Bill…