Latest News
Science & Tools
Two-phase computational pipeline yields high-affinity de novo BMP-2 binders for bone regeneration
Key Takeaways By combining Rosetta-based motif grafting with deep-learning tools like RFdiffusion, ProteinMPNN, and AlphaFold2, a two-phase approach successfully generated…
De Novo Protein Design Overcomes Gene Editing Limits to Sustain CAR-T and TCR-T Cell Function
Key Takeaways De novo designed proteins bind and modulate entire target families simultaneously, bypassing the translational hurdles of multi-allele gene…
New OpenBind-0 model and dataset benchmark co-folding tools in drug discovery
Key Takeaways OpenBind-0 (OB0) is a fully open-source co-folding model built on OpenFold3, trained on Protein Data Bank (PDB) data,…
Documentation & Tutorials
ML Protein Design Bootcamp Now Available on YouTube
Hosted in November 2025 by the University of California Davis, this course provides a practical, beginner-friendly overview of modern AI/ML…
RFD3 Tutorials Are Here!
We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in the Foundry documentation! Whether you’re…
Documentation Playbook Now Available
The Documentation Playbook is a new guide designed to make writing and maintaining documentation for your software projects clearer and…
Events
Coding, Collaboration, and Camaraderie: REU Trainees’ Introductory Bootcamp 2026
Featured image is of Code School 2026 attendees, including REU trainees, instructors Nate Felbinger and Miranda Simpson, teacher assistants Briana…
Brazil’s Largest Open Science Event Introduces Thousands to Protein Design with Foldit
For the second year in a row, Brazil’s largest open science event introduced thousands of children and families to protein…
Motivated Trainees and Tutors Shine at FEBS Advanced Practical Course
On April 19-24, 2026, 36 international participants gathered in Blankenberge, Belgium, for the FEBS Advanced Practical Course: Generative AI for…
Community News
Science, Connection, and Community: Summer RosettaCon 2026 Recap
Featured image is a group photo of Summer RosettaCon 2026 in-person attendees. With over 600 in-person and virtual attendees, 56…
Speed Up PyRosetta Development with Autocompletion and Type Checking
By Harrison Truscott PyRosetta, the Python interface to the Rosetta binary, now comes packaged with type stub files (.pyi). These…
Let’s Get Social: New Ways to Connect with @RosettaCommons
Rosetta Commons is a community based on sharing scientific discoveries and fostering collaborations to advance our understanding of protein design…