Latest News
Science & Tools
New OpenBind-0 model and dataset benchmark co-folding tools in drug discovery
Key Takeaways OpenBind-0 (OB0) is a fully open-source co-folding model built on OpenFold3, trained on Protein Data Bank (PDB) data,…
Integrating Mass Spectrometry Restraints into Rosetta and AlphaFold Modeling Pipelines
Key Takeaways Integrating mass spectrometry data with computational modeling platforms like Rosetta and AlphaFold2 improves the accuracy of protein structure…
Debating the balance between model openness and biosecurity guardrails
Key Takeaways The scientific community is currently debating how to balance open research with biosecurity protections when it comes to…
Documentation & Tutorials
ML Protein Design Bootcamp Now Available on YouTube
Hosted in November 2025 by the University of California Davis, this course provides a practical, beginner-friendly overview of modern AI/ML…
RFD3 Tutorials Are Here!
We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in the Foundry documentation! Whether you’re…
Documentation Playbook Now Available
The Documentation Playbook is a new guide designed to make writing and maintaining documentation for your software projects clearer and…
Events
Immunogen Design Workshop Hosted by the Meiler Lab Cultivated Collaborations
On April 13 – 15, 2026, fifteen participants from as far away as South Korea gathered at Vanderbilt University to…
Megathon 2026: One week, Two Hackathons, 10 Tutorials, and 16 Curated Datasets
Against a backdrop of blue skies, green palm trees, and white sandy beaches, Megathon 2026 became Rosetta Commons’s first ever…
Registrations are now open for European RosettaCon 2026
The registrations for the 5th European RosettaCon – Crossing Boundaries with Protein Design, taking place October 28–30, 2026 at the…
Community News
Speed Up PyRosetta Development with Autocompletion and Type Checking
By Harrison Truscott PyRosetta, the Python interface to the Rosetta binary, now comes packaged with type stub files (.pyi). These…
Let’s Get Social: New Ways to Connect with @RosettaCommons
Rosetta Commons is a community based on sharing scientific discoveries and fostering collaborations to advance our understanding of protein design…
Rosetta Commons Run (rc-run) Now Available
We are pleased to announce a new Rosetta Commons workflow optimization tool: rc-run. rc-run (invoked as rc) is a command-line…