Latest News
Science & Tools
High-Throughput Protein Purification: From Linear DNA to Pure Protein in Three Days
Key Takeaways An engineered His-tagged SUMO protease was developed to release SUMO-tagged proteins directly from nickel-charged magnetic beads. This on-bead…
Two-phase computational pipeline yields high-affinity de novo BMP-2 binders for bone regeneration
Key Takeaways By combining Rosetta-based motif grafting with deep-learning tools like RFdiffusion, ProteinMPNN, and AlphaFold2, a two-phase approach successfully generated…
De Novo Protein Design Overcomes Gene Editing Limits to Sustain CAR-T and TCR-T Cell Function
Key Takeaways De novo designed proteins bind and modulate entire target families simultaneously, bypassing the translational hurdles of multi-allele gene…
Documentation & Tutorials
How to Build a Model with AtomWorks: A Step-by-Step Guided Tutorial
Whether you’re training your first machine learning model or your tenth, preparing your data and building the infrastructure around your…
ML Protein Design Bootcamp Now Available on YouTube
Hosted in November 2025 by the University of California Davis, this course provides a practical, beginner-friendly overview of modern AI/ML…
RFD3 Tutorials Are Here!
We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in the Foundry documentation! Whether you’re…
Events
Registrations are now open for European RosettaCon 2026
The registrations for the 5th European RosettaCon – Crossing Boundaries with Protein Design, taking place October 28–30, 2026 at the…
Summer RosettaCon 2026 registration is now open
We are pleased to announce that Summer RosettaCon 2026 will take place at the University of Washington in Seattle from…
Registration open: Immunogen design workshop at Vanderbilt
The Meiler Lab at Vanderbilt University will host an in-person workshop, Computationally Guided Immunogen Design with Rosetta and ML Tools,…
Community News
Science, Connection, and Community: Summer RosettaCon 2026 Recap
Featured image is a group photo of Summer RosettaCon 2026 in-person attendees. With over 600 in-person and virtual attendees, 56…
Speed Up PyRosetta Development with Autocompletion and Type Checking
By Harrison Truscott PyRosetta, the Python interface to the Rosetta binary, now comes packaged with type stub files (.pyi). These…
Let’s Get Social: New Ways to Connect with @RosettaCommons
Rosetta Commons is a community based on sharing scientific discoveries and fostering collaborations to advance our understanding of protein design…