Latest News
Science & Tools
Stable de novo protein design via joint conformational landscape and sequence optimization
Why this research matters Protein design only works if a designed sequence reliably folds into the intended structure. In practice,…
Designing new enzymes around catalytic arrays with Riff-Diff
Markus Braun, Adrian Tripp, and colleagues from the Oberdorfer lab at Graz University of Technology developed Riff-Diff, a computational pipeline…
RFdiffusion3 is Now Available in foundry
The RFdiffusion3 (RFD3) training and inference code is now available through foundry. This third-generation model builds on RFdiffusion1 and RFdiffusion2,…
Documentation & Tutorials
ML Protein Design Bootcamp Now Available on YouTube
Hosted in November 2025 by the University of California Davis, this course provides a practical, beginner-friendly overview of modern AI/ML…
RFD3 Tutorials Are Here!
We’re excited to announce that three introductory tutorials for RFdiffusion3 (RFD3) are now available in the Foundry documentation! Whether you’re…
Documentation Playbook Now Available
The Documentation Playbook is a new guide designed to make writing and maintaining documentation for your software projects clearer and…
Events
Summer 2026 Workshop Registrations Now Open
Two exciting week-long workshops this summer are now accepting applications. On July 20 – 24, 2026, the ML & Rosetta…
Immunogen Design Workshop Hosted by the Meiler Lab Cultivated Collaborations
On April 13 – 15, 2026, fifteen participants from as far away as South Korea gathered at Vanderbilt University to…
Megathon 2026: One week, Two Hackathons, 10 Tutorials, and 16 Curated Datasets
Against a backdrop of blue skies, green palm trees, and white sandy beaches, Megathon 2026 became Rosetta Commons’s first ever…
Community News
Speed Up PyRosetta Development with Autocompletion and Type Checking
By Harrison Truscott PyRosetta, the Python interface to the Rosetta binary, now comes packaged with type stub files (.pyi). These…
Let’s Get Social: New Ways to Connect with @RosettaCommons
Rosetta Commons is a community based on sharing scientific discoveries and fostering collaborations to advance our understanding of protein design…
Rosetta Commons Run (rc-run) Now Available
We are pleased to announce a new Rosetta Commons workflow optimization tool: rc-run. rc-run (invoked as rc) is a command-line…